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Tdark Uncharacterized protein C18orf8

This gene encodes a colon cancer associated protein. [provided by RefSeq, Jan 2013]

 Comments

Property Summary

NCBI Gene PubMed Count 6
PubMed Score 0.18
PubTator Score 7.50

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (1)

Disease Target Count P-value
osteosarcoma 7933 2.9e-07
intraductal papillary-mucinous adenoma (IPMA) 2956 3.2e-03

Expression

  Differential Expression (2)

Disease log2 FC p
osteosarcoma -1.694 2.9e-07
intraductal papillary-mucinous adenoma (... 1.200 3.2e-03

Synonym

Accession Q96DM3 Q9BU17 Q9Y5M0
Symbols MIC1
Mic-1
HsT2591

Gene

C18orf8

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (2)

 GO Component (1)

 Compartment GO Term (24)

See all...

 GWAS Trait (1)

 HCA RNA Cell Line (56)

See all...

AA Sequence 

MGEEDYYLELCERPVQFEKANPVNCVFFDEANKQVFAVRSGGATGVVVKGPDDRNPISFRMDDKGEVKCI      1 - 70
KFSLENKILAVQRTSKTVDFCNFIPDNSQLEYTQECKTKNANILGFCWTSSTEIVFITDQGIEFYQVLPE     71 - 140
KRSLKLLKSHNLNVNWYMYCPESAVILLSTTVLENVLQPFHFRAGTMSKLPKFEIELPAAPKSTKPSLSE    141 - 210
RDIAMATIYGQLYVLFLRHHSRTSNSTGAEVVLYHLPREGACKKMHILKLNRTGKFALNVVDNLVVVHHQ    211 - 280
DTETSVIFDIKLRGEFDGSVTFHHPVLPARSIQPYQIPITGPAAVTSQSPVPCKLYSSSWIVFQPDIIIS    281 - 350
ASQGYLWNLQVKLEPIVNLLPDKGRLMDFLLQRKECKMVILSVCSQMLSESDRASLPVIATVFDKLNHEY    351 - 420
KKYLDAEQSYAMAVEAGQSRSSPLLKRPVRTQAVLDQSDVYTHVLSAFVEKKEMPHKFVIAVLMEYIRSL    421 - 490
NQFQIAVQHYLHELVIKTLVQHNLFYMLHQFLQYHVLSDSKPLACLLLSLESFYPPAHQLSLDMLKRLST    491 - 560
ANDEIVEVLLSKHQVLAALRFIRGIGGHDNISARKFLDAAKQTEDNMLFYTIFRFFEQRNQRLRGSPNFT    561 - 630
PGEHCEEHVAFFKQIFGDQALMRPTTF                                               631 - 657
//

Text Mined References (7)

PMID Year Title
27779672 2016 Knockdown of macrophage inhibitory cytokine-1 in RPMI-8226 human multiple myeloma cells inhibits osteoclastic differentiation through inhibiting the RANKL-Erk1/2 signaling pathway.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
17897319 2007 Integral and associated lysosomal membrane proteins.
17081983 2006 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.