Property Summary

NCBI Gene PubMed Count 5
PubMed Score 1.50
PubTator Score 1.50

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (10)

Disease log2 FC p
chronic lymphocytic leukemia 1.133 2.6e-04
osteosarcoma -1.882 1.3e-07
glioblastoma -1.200 1.0e-04
medulloblastoma, large-cell -1.300 2.7e-04
pancreatic ductal adenocarcinoma liver m... 1.100 3.3e-02
adult high grade glioma -1.400 6.9e-05
pilocytic astrocytoma -1.300 3.0e-06
lung carcinoma 1.200 1.4e-21
non-small cell lung carcinoma 1.100 5.3e-35
pituitary cancer 1.300 2.5e-06

Synonym

Accession Q8N6T0 Q9H677
Symbols TOP6BL
TOPOVIBL

Gene

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

AA Sequence

MEGTAVAVFEILRFLIIHWKCDIDVSKGALLEGQLVISIEGLNSKHQANALHCVTTVASAGSLFGGMVLK      1 - 70
KFLKEIQSILPGISAKLTWTSEEGSYSQDMTGVTPFQMIFEVDEKPRTLMTDCLVIKHFLRKIIMVHPKV     71 - 140
RFHFSVKVNGILSTEIFGVENEPTLNLGNGIALLVDSQHYVRPNFGTIESHCSRIHPVLGHPVMLFIPED    141 - 210
VAGMDLLGELILTPAAALCPSPKVSSNQLNRISSVSIFLYGPLGLPLILSTWEQPMTTFFKDTSSLVDWK    211 - 280
KYHLCMIPNLDLNLDRDLVLPDVSYQVESSEEDQSQTMDPQGQTLLLFLFVDFHSAFPVQQMEIWGVYTL    281 - 350
LTTHLNAILVESHSVVQGSIQFTVDKVLEQHHQAAKAQQKLQASLSVAVNSIMSILTGSTRSSFRKMCLQ    351 - 420
TLQAADTQEFRTKLHKVFREITQHQFLHHCSCEVKQQLTLEKKDSAQGTEDAPDNSSLELLADTSGQAEN    421 - 490
KRLKRGSPRIEEMRALRSARAPSPSEAAPRRPEATAAPLTPRGREHREAHGRALAPGRASLGSRLEDVLW    491 - 560
LQEVSNLSEWLSPSPGP                                                         561 - 577
//

Text Mined References (8)

PMID Year Title
26917764 2016 The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation.
21926972 2011 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
18160775 2007 The molecular basis of the folate-sensitive fragile site FRA11A at 11q13.
16554811 2006 Human chromosome 11 DNA sequence and analysis including novel gene identification.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
8125298 1994 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.