Tdark BICDL1 BICD family-like cargo adapter 1

Protein Summary

Description

Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity).

Uniprot Accession IDs

• Q6ZP65
• A8MUC8
• B4DWL0
• B5MDJ0
• O95000

Gene Name

• BICDL1

Ensembl ID

• ENST00000397558
• ENSP00000380690
• ENSG00000135127

Symbol

• BICDR1
• CCDC64
• BICDR1
• CCDC64
• BICDR-1
• CCDC64A
• H_267D11.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.19   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 22   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.19   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0