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Tbio
BAALC
Brain and acute leukemia cytoplasmic protein

Protein Summary
Description
May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297574
  • ENSP00000297574
  • ENSG00000164929
  • ENST00000306391
  • ENSP00000302559
  • ENST00000309982
  • ENSP00000312457
  • ENST00000330955
  • ENSP00000331579
  • ENST00000438105
  • ENSP00000395024
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
PubMedID
0.75
microRNA
0.62
kinase perturbation
0.6
tissue sample
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.81   (req: < 5)
Gene RIFs: 41   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.81   (req: >= 5)
Gene RIFs: 41   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0