ATOH7
Protein atonal homolog 7
Protein Summary
Transcription factor involved in the differentiation of retinal ganglion cells. This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]
- ENST00000373673
- ENSP00000362777
- ENSG00000179774
- ATH5
- BHLHA13
- Math5
- NCRNA
- RNANC
- PHPVAR
- bHLHa13
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.6 | ||
biological process | 0.51 | ||
cell line | 0.5 | ||
transcription factor | 0.5 | ||
PubMedID | 0.49 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 222.21 (req: < 5)
Gene RIFs: 24 (req: <= 3)
Antibodies: 210 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 222.21 (req: >= 5)
Gene RIFs: 24 (req: > 3)
Antibodies: 210 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0