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Tbio
ATMIN
ATM interactor

Protein Summary
Description
Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299575
  • ENSP00000299575
  • ENSG00000166454
  • ENST00000564241
  • ENSP00000463478
  • ENST00000566488
  • ENSP00000455497

Symbol
  • KIAA0431
  • ZNF822
  • ASCIZ
  • ZNF822
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
microRNA
0.68
tissue sample
0.68
transcription factor perturbation
0.68
cell type or tissue
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.57   (req: < 5)
Gene RIFs: 22   (req: <= 3)
Antibodies: 122   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.57   (req: >= 5)
Gene RIFs: 22   (req: > 3)
Antibodies: 122   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0