Protein Summary
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:18270207, PubMed:19665976, PubMed:27619977).
- ENST00000378954
- ENSP00000368237
- ENSG00000119787
- ENST00000402054
- ENSP00000384062
- ENST00000419554
- ENSP00000415336
- ENST00000452935
- ENSP00000390743
- ARL6IP2
- aip-2
- ARL3IP2
- ARL6IP2
- atlastin2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.94 | ||
molecular function | 0.93 | ||
microRNA | 0.78 | ||
small molecule perturbation | 0.75 | ||
histone modification site profile | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 30.66 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 113 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 30.66 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 113 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0