| Tbio | Achaete-scute homolog 3 |
Transcriptional repressor. Inhibits myogenesis (By similarity).
Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 6.4e-08 |
| osteosarcoma | 7950 | 5.0e-06 |
| medulloblastoma, large-cell | 6241 | 7.9e-06 |
| psoriasis | 6694 | 7.2e-04 |
| adult high grade glioma | 3801 | 2.1e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Ascariasis | 7 | 3.866 | 1.9 |
| Leukoencephalopathy with vanishing white matter | 20 | 3.318 | 1.7 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | 1.100 | 2.1e-03 |
| medulloblastoma, large-cell | 1.400 | 7.9e-06 |
| osteosarcoma | 1.400 | 5.0e-06 |
| ovarian cancer | 1.200 | 6.4e-08 |
| psoriasis | 1.300 | 7.2e-04 |
