Tbio | Ecto-ADP-ribosyltransferase 3 |
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Comments
Disease | Target Count | P-value |
---|---|---|
atypical teratoid / rhabdoid tumor | 5112 | 7.9e-08 |
Duchenne muscular dystrophy | 601 | 9.4e-08 |
limb girdle muscular dystrophy 2A | 213 | 2.2e-05 |
glioblastoma | 5792 | 1.6e-04 |
group 4 medulloblastoma | 1855 | 5.0e-04 |
Becker muscular dystrophy | 191 | 5.7e-04 |
Pick disease | 1894 | 8.3e-04 |
active Crohn's disease | 922 | 3.5e-03 |
astrocytic glioma | 2597 | 7.9e-03 |
active ulcerative colitis | 764 | 9.9e-03 |
pituitary cancer | 1972 | 1.1e-02 |
adult high grade glioma | 3801 | 1.6e-02 |
oligodendroglioma | 2850 | 2.0e-02 |
primitive neuroectodermal tumor | 3035 | 2.4e-02 |
subependymal giant cell astrocytoma | 2287 | 4.6e-02 |
facioscapulohumeral dystrophy | 288 | 4.7e-02 |
ependymoma | 4679 | 4.9e-02 |
Disease | Target Count | Z-score | Confidence |
---|---|---|---|
Arts syndrome | 26 | 4.969 | 2.5 |
Esophageal candidiasis | 2 | 3.63 | 1.8 |
Azoospermia | 110 | 3.433 | 1.7 |
Disease | log2 FC | p |
---|---|---|
active Crohn's disease | 3.029 | 3.5e-03 |
active ulcerative colitis | 1.790 | 9.9e-03 |
adult high grade glioma | -1.200 | 1.6e-02 |
astrocytic glioma | -2.400 | 7.9e-03 |
atypical teratoid / rhabdoid tumor | -2.200 | 7.9e-08 |
Becker muscular dystrophy | -1.150 | 5.7e-04 |
Duchenne muscular dystrophy | -1.513 | 9.4e-08 |
ependymoma | -2.100 | 4.9e-02 |
facioscapulohumeral dystrophy | 1.800 | 4.7e-02 |
glioblastoma | -1.600 | 1.6e-04 |
group 4 medulloblastoma | -1.800 | 5.0e-04 |
limb girdle muscular dystrophy 2A | -1.277 | 2.2e-05 |
oligodendroglioma | -2.000 | 2.0e-02 |
Pick disease | -1.100 | 8.3e-04 |
pituitary cancer | -1.300 | 1.1e-02 |
primitive neuroectodermal tumor | -1.600 | 2.4e-02 |
subependymal giant cell astrocytoma | -1.006 | 4.6e-02 |
Species | Source | Disease |
---|---|---|
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
Inparanoid OMA EggNOG | ||
OMA EggNOG |
MKTGHFEIVTMLLATMILVDIFQVKAEVLDMADNAFDDEYLKCTDRMEIKYVPQLLKEEKASHQQLDTVW 1 - 70 ENAKAKWAARKTQIFLPMNFKDNHGIALMAYISEAQEQTPFYHLFSEAVKMAGQSREDYIYGFQFKAFHF 71 - 140 YLTRALQLLRKPCEASSKTVVYRTSQGTSFTFGGLNQARFGHFTLAYSAKPQAANDQLTVLSIYTCLGVD 141 - 210 IENFLDKESERITLIPLNEVFQVSQEGAGNNLILQSINKTCSHYECAFLGGLKTENCIENLEYFQPIYVY 211 - 280 NPGEKNQKLEDHSEKNWKLEDHGEKNQKLEDHGVKILEPTQIPGMKIPEPFPLPEDKSQGNINNPTPGPV 281 - 350 PVPGPKSHPSASSGKLLLPQFGMVIILISVSAINLFVAL 351 - 389 //