You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ARHGAP40
Rho GTPase-activating protein 40

Protein Summary
Description
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373345
  • ENSP00000362442
  • ENSG00000124143

Symbol
  • C20orf95
  • C20orf95
  • dJ1100H13.4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.63
disease
0.55
protein complex
0.41
microRNA
0.4
phenotype
0.35


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.32   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 55   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.32   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0