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Tbio Rho GTPase-activating protein 39


 Comments

Property Summary

NCBI Gene PubMed Count 8
PubMed Score 2.64
PubTator Score 0.96

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
osteosarcoma 7933 5.8e-04
invasive ductal carcinoma 2950 9.2e-03
Disease Target Count Z-score Confidence
Mastitis 48 3.492 1.7

Expression

  Differential Expression (2)

Disease log2 FC p
osteosarcoma -1.476 5.8e-04
invasive ductal carcinoma 1.100 9.2e-03

Synonym

Accession Q9C0H5 B4E1I1
Symbols CrGAP
Vilse

Gene

ARHGAP39

PANTHER Protein Class (1)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG Inparanoid

 UniProt Keyword (7)

 GO Function (1)

 GO Component (3)

 GO Process (2)

 Compartment GO Term (16)

See all...

 GWAS Trait (1)

 HCA RNA Cell Line (54)

See all...

Pathway (8)

Protein-protein Interaction (64)

RHOD   RASGRF2   MCF2L   ARHGEF11   ARHGEF9   KALRN   SRGAP2   TRIO   SLIT2   PLEKHG5   RHOBTB1   RHOC   MCF2   RAC2   VAV1   RHOQ   GDI1   GDI2   VAV2   RAC3   CDC42   RHOA   RHOB   RAC1   RHOG   SOS1   SOS2   AKAP13   ABR   TIAM1   ARHGEF7   RHOH   ITSN1   FGD3   OBSCN   ARHGEF16   ARHGEF18   RHOU   NET1   SRGAP1   FGD2   TIAM2   ARHGEF19   RHOT2   RHOT1   NGEF   PREX1   ARHGEF1   ARHGEF2   ARHGEF26   RHOV   FGD4   ARHGEF17   ARHGDIG   RHOBTB2   RHOJ   PLEKHG2   ECT2   RHOF   ARHGEF4   ARHGEF3   ARHGEF12   VAV3   ROBO1  

AA Sequence 

MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVRIKRTSENQWW      1 - 70
ELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASAESSPGRGSSVSREGSTSSSL     71 - 140
EPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLEKDYEIYRDYSADGQLLHYRTSSLRWNSGAK    141 - 210
ERMLIKVADREPSFLAAQGNGYAPDGPPGVRSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAE    211 - 280
LPGSSSPLLAQPRKPSGDSQPSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPG    281 - 350
RKPRPFLQPNKQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP    351 - 420
NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQDTLSSTGYSPG    421 - 490
TRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAEGEAEGARGAAEPFLAQARLA    491 - 560
WEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVVRAFSEDEALAQQENRHWRRGTFEKLGFPQI    561 - 630
LLEKSVSVQTNLASPEPYLHPSQSEDLAACAQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASK    631 - 700
HFNKHTQGLFRRKVSIANMLAWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEV    701 - 770
ATKGWSVQGLRDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK    771 - 840
GVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPW    841 - 910
VQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPH    911 - 980
EFYEQCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQS    981 - 1050
DDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL                                        1051 - 1083
//

Text Mined References (16)

PMID Year Title
25201988 2014 Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
24665060 2014 Genome-wide association study of smoking behaviours among Bangladeshi adults.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19690332 2009 Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18691976 2008 Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
16421571 2006 DNA sequence and analysis of human chromosome 8.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15755809 2005 Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion.
15302935 2004 Large-scale characterization of HeLa cell nuclear phosphoproteins.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11214970 2000 Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.