Tbio ANXA2R Annexin-2 receptor

Protein Summary

Description

May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.

Uniprot Accession IDs

• Q3ZCQ2
• Q8NHX5

Gene Name

• ANXA2R

Ensembl ID

• ENST00000314890
• ENSP00000315915
• ENSG00000177721
• ENST00000616064
• ENSP00000479862

Symbol

• AX2R
• C5orf39
• AX2R
• AXIIR
• C5orf39

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.62
tissue	0.62
tissue sample	0.6
histone modification site profile	0.58
cell type or tissue	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.69   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 88   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.69   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 88   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0