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Tbio
ANKS1A
Ankyrin repeat and SAM domain-containing protein 1A

Protein Summary
Description
Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360359
  • ENSP00000353518
  • ENSG00000064999

Symbol
  • ANKS1
  • KIAA0229
  • ODIN
  • ANKS1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.96
protein domain
0.92
disease perturbation
0.87
transcription factor binding site profile
0.87
histone modification site profile
0.76


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 59.59   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 94   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 59.59   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 94   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0