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Tbio
ANGPTL6
Angiopoietin-related protein 6

Protein Summary
Description
May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253109
  • ENSP00000253109
  • ENSG00000130812
  • ENST00000592641
  • ENSP00000467930

Symbol
  • AGF
  • ARP5
  • AGF
  • ARP5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.63
protein domain
0.58
tissue sample
0.58
cell type or tissue
0.54
disease
0.54


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 262.47   (req: < 5)
Gene RIFs: 23   (req: <= 3)
Antibodies: 172   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 262.47   (req: >= 5)
Gene RIFs: 23   (req: > 3)
Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0