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Tbio
ANGPTL1
Angiopoietin-related protein 1

Protein Summary
Description
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000234816
  • ENSP00000234816
  • ENSG00000116194
  • ENST00000367629
  • ENSP00000356601

Symbol
  • ANG3
  • ANGPT3
  • ARP1
  • ANG3
  • ARP1
  • AngY
  • ANGPT3
  • UNQ162
  • dJ595C2.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.92
microRNA
0.72
virus perturbation
0.59
protein domain
0.58
gene perturbation
0.56


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.54   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 364   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.54   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 364   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0