Tdark ALLC Probable allantoicase

Protein Summary

Description

The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. Allantoicase (EC 3.5.3.4) participates in the uric acid degradation pathway. Its enzymatic activity, like that of urate oxidase (MIM 191540), was lost during vertebrate evolution.[supplied by OMIM, Nov 2008]

Uniprot Accession IDs

• Q8N6M5
• B4DY77
• Q53T95
• Q5RL81
• Q96RE6
• Q9NZA7

Gene Name

• ALLC

Ensembl ID

• ENST00000252505
• ENSP00000252505
• ENSG00000151360

Symbol

• ALC

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.94
gene perturbation	0.88
disease	0.7
tissue	0.59
cell type or tissue	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 433.09   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 0   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 433.09   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0