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Tbio
ALG9
Alpha-1,2-mannosyltransferase ALG9

Protein Summary
Description
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides. This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398006
  • ENSP00000381090
  • ENSG00000086848
  • ENST00000531154
  • ENSP00000435517
  • ENST00000614444
  • ENSP00000484200
  • ENST00000616540
  • ENSP00000482437

Symbol
  • DIBD1
  • CDG1L
  • DIBD1
  • GIKANIS
  • LOH11CR1J
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
virus perturbation
0.68
transcription factor binding site profile
0.64
cellular component
0.6
pathway
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.95   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.95   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0