Tdark ADCK5 Uncharacterized aarF domain-containing protein kinase 5

Protein Summary

Description

The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

Uniprot Accession IDs

• Q3MIX3
• B3KS46
• Q5U4P1
• Q6P2S4
• Q8N5V3

Gene Name

• ADCK5

Ensembl ID

• ENST00000308860
• ENSP00000310547
• ENSG00000173137
• ENST00000645968
• ENSP00000494807
• ENSG00000285451

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.84
transcription factor binding site profile	0.76
kinase perturbation	0.6
transcription factor	0.59
virus perturbation	0.59

Protein Classes

PANTHER Classes

Protein / ... / Serine Protease / Uncharacterized Aarf Domain-containing Protein Kinase 5

DTO Classes

Protein / Kinase / Protein Kinase / Atypical Group / Abc1 Family / Abc1-b Subfamily / Uncharacterized Aarf Domain-containing Protein Kinase 5

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.25   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 171   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.25   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 171   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0