Tbio ADCK2 Uncharacterized aarF domain-containing protein kinase 2

Protein Summary

Description

The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

Uniprot Accession IDs

• Q7Z695
• Q96CN6
• Q9Y6T5

Gene Name

• ADCK2

Ensembl ID

• ENST00000072869
• ENSP00000072869
• ENSG00000133597

Symbol

• AARF
• AARF

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
cell type or tissue	0.72
histone modification site profile	0.72
cell line	0.56
tissue sample	0.56

Protein Classes

DTO Classes

Protein / Kinase / Protein Kinase / Atypical Group / Abc1 Family / Abc1-c Subfamily / Uncharacterized Aarf Domain-containing Protein Kinase 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.76   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 160   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.76   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 160   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0