ADAM20
Disintegrin and metalloproteinase domain-containing protein 20
Protein Summary
May be involved in sperm maturation and/or fertilization. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene is testis-specific. [provided by RefSeq, Jul 2008]
- ENST00000256389
- ENSP00000256389
- ENSG00000134007
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
co-expressed gene | 0.99 | ||
gene perturbation | 0.98 | ||
protein domain | 0.85 | ||
kinase perturbation | 0.71 | ||
cell type or tissue | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.56 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 166 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.56 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 166 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0