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Tbio
ACSM1
Acyl-coenzyme A synthetase ACSM1, mitochondrial

Protein Summary
Description
Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro). Functions as GTP-dependent lipoate-activating enzyme that generates the substrate for lipoyltransferase (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307493
  • ENSP00000301956
  • ENSG00000166743
  • ENST00000519745
  • ENSP00000428650
  • ENST00000520010
  • ENSP00000428047

Symbol
  • BUCS1
  • LAE
  • MACS1
  • BUCS1
  • MACS1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.96
tissue sample
0.71
cell type or tissue
0.65
gene perturbation
0.62
cellular component
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.76   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.76   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 16
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0