You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ABLIM3
Actin-binding LIM protein 3

Protein Summary
Description
May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients. [provided by RefSeq, Sep 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309868
  • ENSP00000310309
  • ENSG00000173210
  • ENST00000326685
  • ENSP00000315841
  • ENST00000504238
  • ENSP00000421183
  • ENST00000506113
  • ENSP00000425394
  • ENST00000517451
  • ENSP00000430150

Symbol
  • KIAA0843
  • HMFN1661
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.86
tissue sample
0.74
biological process
0.66
transcription factor binding site profile
0.64
microRNA
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.48   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 143   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.48   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 143   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0