Protein Summary
This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016]
- ENST00000222800
- ENSP00000222800
- ENSG00000106077
- ENST00000357419
- ENSP00000392945
- ENST00000395147
- ENSP00000378579
- ENST00000437775
- ENSP00000416970
- WBSCR21
- PP1226
- WBSCR21
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.9 | ||
histone modification site profile | 0.85 | ||
kinase perturbation | 0.71 | ||
transcription factor | 0.63 | ||
cell type or tissue | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.39 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 115 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 13.39 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 115 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0