GOLGA8A
Golgin subfamily A member 8A
Protein Summary
May be involved in maintaining Golgi structure. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked, flattened membrane sacs referred to as cisternae. Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins constitute a family of proteins which are localized to the Golgi. This gene encodes a golgin which structurally resembles its family member GOLGA2, suggesting that they may share a similar function. There are many similar copies of this gene on chromosome 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
- ENST00000359187
- ENSP00000352111
- ENSG00000175265
- ENST00000432566
- ENSP00000402791
- KIAA0855
- GM88
- GOLGA8B
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.76 | ||
tissue | 0.76 | ||
small molecule perturbation | 0.7 | ||
disease | 0.64 | ||
tissue sample | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.63 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 47 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 4.63 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 47 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0