Tbio PCNX2 Pecanex-like protein 2

Protein Summary

Description

May play a role in tumorigenesis of colorectal carcinomas with high microsatellite instability (MSI-H). This gene contains coding mononucleotide repeats that are associated with tumors of high mcrosatellite instability (MSI-H). Defects in this gene are involved in the tumorigenesis of MSI-H colorectal carcinomas. [provided by RefSeq, Jun 2016]

Uniprot Accession IDs

• A6NKB5
• O43162
• Q5T9Z8
• Q5TDF1
• Q8TEP4
• Q96HP9
• Q9HAL8

Gene Name

• PCNX2

Ensembl ID

• ENST00000258229
• ENSP00000258229
• ENSG00000135749
• ENST00000344698
• ENSP00000340759

Symbol

• KIAA0435
• PCNXL2
• PCNXL2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.65   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 48   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.65   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0