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Tdark
TBC1D3F
TBC1 domain family member 3F

Protein Summary
Description
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000614193
  • ENSP00000477822
  • ENSG00000282087
  • ENST00000621026
  • ENSP00000482590
  • ENSG00000275954

Symbol
  • TBC1D3E
  • TBC1D3
  • TBC1D3G
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
tissue sample
0.65
cell type or tissue
0.61
cell line
0.54
tissue
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.15   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.15   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0