Tdark GOLGA6B Golgin subfamily A member 6B

Protein Summary

Description

This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, which are greater than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosomal rearrangements that underlie genomic disease. This gene is a member of the golgin gene family, whose protein products localize to the Golgi apparatus. The majority of the related gene copies are thought to be transcribed pseudogenes. It is not known whether this gene is a pseudogene or if it encodes a golgin protein. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• A6NDN3
• A8MYY7

Gene Name

• GOLGA6B

Ensembl ID

• ENST00000421285
• ENSP00000408132
• ENSG00000215186

Symbol

• GOLGA
• GOLGA
• GOLGA6D

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.74
cell line	0.41
cellular component	0.41
disease	0.34
interacting protein	0.31

Protein Classes

PANTHER Classes

Protein / Membrane Traffic Protein / Golgin Subfamily A Member 6b

DTO Classes

Protein / Transporter / Golgin Subfamily A Member 6b

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.08   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 86   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.08   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0