Property Summary

NCBI Gene PubMed Count 5
PubMed Score 6.32
PubTator Score 1.25

Knowledge Summary


No data available


  Disease Sources (4)

Disease Target Count
Obesity 616
Disease Target Count P-value
lung carcinoma 2844 9.99079399073343E-45
non-small cell lung cancer 2798 8.54967070212138E-9
pituitary cancer 1972 3.66879483126394E-6
adrenocortical carcinoma 1427 5.82990561596148E-6
sonic hedgehog group medulloblastoma 1482 1.18726110887152E-4
interstitial cystitis 2299 2.99801135664631E-4
subependymal giant cell astrocytoma 2287 9.64270084714121E-4
head and neck cancer 270 0.00179367054967785
cystic fibrosis 1670 0.00399746708235389
glioblastoma 5572 0.00508773537924311
non-inflammatory breast cancer 208 0.00718821642963845
fibroadenoma 557 0.0246810906334432
head and neck cancer and chronic obstructive pulmonary disease 237 0.024695993339942
ovarian cancer 8492 0.0315514632566902
Disease Target Count Z-score Confidence
Parkinson's disease 364 0.0 1.0
Disease Target Count Z-score Confidence
Endometritis 21 3.093 1.5


  Differential Expression (14)


Accession A0PJW8 A0PJW9 B9EIK6


PANTHER Protein Class (1)

  Ortholog (12)

Gene RIF (2)

25680934 DAPL1 plays a role in epithelial differentiation and may be involved in apoptotic processes thereby suggesting a possible novel pathway in AMD pathogenesis.
20800603 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

NYKFPATVHMAHQKPTPALEKVVPLKRIYIIQQPRKC                                      71 - 107

Text Mined References (7)

PMID Year Title
25680934 2015 A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD).
23251661 2012 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
20800603 2010 Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
15920738 2006 EEDA: a protein associated with an early stage of stratified epithelial differentiation.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12107413 2002 Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants.