Currently the ligands view is a work in progress and should not be considered a definitive resource yet

Library

Selleck Bioactive Compound 3 | 855
Selleck FDA Approved Drug 3 | 410
NCATS MIPE 2 | 567

Development Level

Tclin 27 | 127,306
Tchem 9 | 103,180

Target Family

Enzyme 11 | 84,773
Ion Channel 10 | 16,308
Non-IDG 10 | 16,032
GPCR 3 | 57,167
Kinase 1 | 33,162
Nuclear Receptor 1 | 6,975

Target

GUCY1A1 5 | 5
GUCY1A2 5 | 5
GUCY1B1 5 | 6
GUCY1B2 5 | 5
CSF3R 4 | 4
CATSPER1 3 | 3
CATSPER2 3 | 3
CATSPER3 3 | 3
CATSPER4 3 | 3
SERPINC1 3 | 9
KCNT2 2 | 2
PLG 2 | 275
PTGER1 2 | 388
PTGER2 2 | 99
PTGS2 2 | 1,543
ACHE 1 | 1,867
AKR1B10 1 | 48
AKR1C2 1 | 38
AKR1C3 1 | 244
AR 1 | 776
CLCNKA 1 | 1
CLCNKB 1 | 1
DRD2 1 | 2,367
DRD3 1 | 2,358
DRD4 1 | 1,272
HTR2A 1 | 1,998
HTR6 1 | 1,944
KCNJ4 1 | 1
KCNN4 1 | 47
KCNQ2 1 | 8
KCNQ3 1 | 5
KCNQ4 1 | 6
KCNQ5 1 | 5
KCNT1 1 | 1
NOD2 1 | 11
NR3C1 1 | 1,478
NR3C2 1 | 160
PAH 1 | 2
PGR 1 | 625
PRKCD 1 | 178
PRKCE 1 | 105
PRKCG 1 | 39
PRKD1 1 | 55
PTGER3 1 | 352
PTGER4 1 | 277
PTGS1 1 | 317
SCN5A 1 | 316
SERPINA6 1 | 20
SHBG 1 | 91
SIGMAR1 1 | 1,848
TRPC5 1 | 1
TRPM4 1 | 2
TRPM8 1 | 334
TTR 1 | 29

Pharmalogical Action

ACTIVATOR 28 | 28
INHIBITOR 471 | 471
AGONIST 405 | 405
ANTAGONIST 314 | 314
BLOCKER 117 | 117
ANTIBODY BINDING 57 | 57
POSITIVE ALLOSTERIC MODULATOR 41 | 41
MODULATOR 19 | 19
OPENER 15 | 15
POSITIVE MODULATOR 14 | 14
PARTIAL AGONIST 12 | 12
INVERSE AGONIST 8 | 8
GATING INHIBITOR 6 | 6
RELEASING AGENT 5 | 5
SUBSTRATE 5 | 5
ALLOSTERIC MODULATOR 4 | 4
NEGATIVE ALLOSTERIC MODULATOR 4 | 4
PHARMACOLOGICAL CHAPERONE 3 | 3
ALLOSTERIC ANTAGONIST 1 | 1
OTHER 1 | 1

Ligand Activity

IC50 5 | 141,067
Ki 3 | 69,787
EC50 2 | 7,763
Kd 1 | 2,644

Ligand Source

CHEMBL 18 | 221,399
IUPHAR 9 | 121
DRUG LABEL 6 | 219
SCIENTIFIC LITERATURE 4 | 251
KEGG DRUG 1 | 44