Currently the ligands view is a work in progress and should not be considered a definitive resource yet

Development Level

Tclin 26
Tchem 8

Target Family

Enzyme 13
Non-IDG 10
Ion Channel 7
GPCR 3
Kinase 1
Nuclear Receptor 1

Pharmalogical Action

ACTIVATOR 27
INHIBITOR 454
AGONIST 399
ANTAGONIST 310
BLOCKER 116
ANTIBODY BINDING 55
POSITIVE ALLOSTERIC MODULATOR 44
MODULATOR 20
OPENER 17
POSITIVE MODULATOR 15
PARTIAL AGONIST 14
INVERSE AGONIST 8
RELEASING AGENT 5
SUBSTRATE 5
NEGATIVE ALLOSTERIC MODULATOR 4
NEGATIVE MODULATOR 3
ALLOSTERIC ANTAGONIST 1
OTHER 1
PHARMACOLOGICAL CHAPERONE 1

Ligand Source

CHEMBL 16
IUPHAR 8
DRUG LABEL 7
SCIENTIFIC LITERATURE 3
KEGG DRUG 1

Ligand Activity

IC50 5
Ki 3
EC50 1
Kd 1

Target

GUCY1A2 5
GUCY1A3 5
GUCY1B2 5
GUCY1B3 5
CSF3R 4
PLG 4
CATSPER1 3
CATSPER2 3
CATSPER3 3
CATSPER4 3
SERPINC1 3
KCNT2 2
PTGER1 2
PTGER2 2
PTGS2 2
ACHE 1
AKR1B10 1
AKR1C2 1
AKR1C3 1
AR 1
DRD2 1
DRD3 1
DRD4 1
HTR2A 1
HTR6 1
KCNJ4 1
KCNT1 1
NOD2 1
NR3C1 1
NR3C2 1
PAH 1
PGR 1
PRKCD 1
PRKCE 1
PRKCG 1
PRKD1 1
PTGER3 1
PTGER4 1
PTGS1 1
SERPINA6 1
SHBG 1
SIGMAR1 1
TRPC5 1
TRPM4 1
TTR 1