Currently the ligands view is a work in progress and should not be considered a definitive resource yet

Development Level

Tclin 46
Tchem 6

Target Family

GPCR 19
Enzyme 12
Nuclear Receptor 8
Ion Channel 6
Non-IDG 4
Transporter 3

Pharmalogical Action

ANTAGONIST 15
INHIBITOR 14
AGONIST 11
BLOCKER 3
POSITIVE ALLOSTERIC MODULATOR 2
ACTIVATOR 1
INVERSE AGONIST 1

Ligand Source

KEGG DRUG 46
CHEMBL 9
IUPHAR 2
DRUG LABEL 1

Ligand Activity

IC50 10
Kd 5
Ki 4

Target

PTGS1 7
PTGS2 7
DRD2 4
HRH1 4
NR3C1 4
ADRA1A 3
ADRA1B 3
CACNA1C 3
CACNA1D 3
CHRM1 3
ADRB1 2
CHRM2 2
CHRM3 2
GABRA1 2
GABRB2 2
GABRG2 2
SHBG 2
SIGMAR1 2
SLC6A2 2
VDR 2
ACE 1
ACHE 1
ADRA1D 1
ADRB2 1
AKR1B10 1
AKR1C2 1
AKR1C3 1
ALOX5 1
AR 1
CHRM4 1
CHRM5 1
DHFR 1
DRD1 1
DRD3 1
DRD4 1
ECE1 1
GABRA2 1
GABRA3 1
GABRA4 1
GABRA5 1
GABRA6 1
GABRB1 1
GABRB3 1
GABRD 1
GABRG1 1
GABRG3 1
HRH2 1
HSD11B1 1
HTR1A 1
HTR2A 1
HTR7 1
KCNT2 1
MME 1
OPRM1 1
PGR 1
PTGDR2 1
PTGER1 1
PTGER2 1
SERPINA6 1
SLC12A1 1
SLC12A2 1
SLC6A3 1
TBXA2R 1
TRPM4 1