warfarin
Ligand Summary
An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.
UNII: 5Q7ZVV76EI
PubChem: 54678486
Guide to Pharmacology: 6853
ChEMBL: CHEMBL1464
DrugCentral: 2847
LyCHI: YHW3JDX1S8JU
Target Activities
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | ||||||
IC50 | ||||||
IC50 | INHIBITOR | |||||