Target Relevance

Mitogen-activated protein kinase 3 Tchem
pIC50 141067 7.74
pIC50 141067 7.74
Vascular endothelial growth factor receptor 1 Tclin
INHIBITOR 471
pKd 2644 7.51
pIC50 141067 7.75
5-hydroxytryptamine receptor 2B Tclin
pKi 69787 7.25
Serine/threonine-protein kinase B-raf Tclin
INHIBITOR 471
pKi 69787 7.66
pIC50 141067 7.58
Mitogen-activated protein kinase kinase kinase 20 Tchem
pKd 2644 8.2
pKd 2644 8.2
Homeodomain-interacting protein kinase 4 Tchem
pKd 2644 8.57
pKd 2644 8.48
Epithelial discoidin domain-containing receptor 1 Tchem
pKd 2644 8.82
pKd 2644 8.82
Epidermal growth factor receptor Tclin
pIC50 141067 8.53
Fibroblast growth factor receptor 1 Tclin
pIC50 141067 8.33
Receptor-type tyrosine-protein kinase FLT3 Tclin
INHIBITOR 471
pKd 2644 8.35
pKd 2644 7.7
Bifunctional epoxide hydrolase 2 Tchem
pIC50 141067 7.92
pIC50 141067 7.92
Platelet-derived growth factor receptor beta Tclin
INHIBITOR 471
pKd 2644 7.43
pIC50 141067 8.0
Mast/stem cell growth factor receptor Kit Tclin
INHIBITOR 471
pKd 2644 7.8
pKd 2644 7.55
Vascular endothelial growth factor receptor 3 Tclin
INHIBITOR 471
pKd 2644 7.8
pKd 2644 7.8
Vascular endothelial growth factor receptor 2 Tclin
INHIBITOR 471
pKi 69787 10.68
pIC50 141067 7.57
Discoidin domain-containing receptor 2 Tchem
pKd 2644 8.18
pIC50 141067 8.16
Macrophage colony-stimulating factor 1 receptor Tclin
pKd 2644 7.55
RAF proto-oncogene serine/threonine-protein kinase Tclin
INHIBITOR 471
pKi 69787 8.22
pIC50 141067 7.61
Proto-oncogene tyrosine-protein kinase receptor Ret Tclin
INHIBITOR 471
pKd 2644 8.13
pKd 2644 7.66

Molecular Definition

Canonical SMILES CNC(=O)C1=CC(OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1
Formula C21H16ClF3N4O3
Molecular Weight 464.83 da
Stereocenters 0/0