pitolisant
Ligand Summary
Pitolisant is a potent, orally active histamine H3-receptor antagonist/inverse agonist which, via its blockade of histamine auto-receptors enhances the activity of brain histaminergic neurons, a major arousal system with widespread projections to the whole brain. Pitolisant also modulates various neurotransmitter systems, increasing acetylcholine, noradrenaline and dopamine release in the brain.
UNII: 4BC83L4PIY
PubChem: 9948102
PubChem: 11551689
Guide to Pharmacology: 8924
ChEMBL: CHEMBL462605
ChEMBL: CHEMBL4164059
DrugCentral: 5048
LyCHI: SGNUZPNGMXH7
Target Activities
28 Activities
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1 – 10 of 28
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