natalizumab
Ligand Summary
A humanized monoclonal immunoglobulin G4 antibody to human INTEGRIN ALPHA4 that binds to the alpha4 subunit of INTEGRIN ALPHA4BETA1 and integrin alpha4beta7. It is used as an IMMUNOLOGIC FACTOR in the treatment of RELAPSING-REMITTING MULTIPLE SCLEROSIS and CROHN'S DISEASE.
ChEMBL: CHEMBL1201607
DrugCentral: 4970
LyCHI: natalizumab
Target Activities
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
ANTIBODY BINDING | ||||||
ANTIBODY BINDING | ||||||
ANTIBODY BINDING | ||||||