molindone
Ligand Summary
An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283)
UNII: RT3Y3QMF8N
PubChem: 23897
Guide to Pharmacology: 207
ChEMBL: CHEMBL460
DrugCentral: 1830
LyCHI: KDAD8KR81WA7
Target Activities
4 Activities
Items per page:
10
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | ANTAGONIST | |||||
Ki | ANTAGONIST | |||||