mitotane
Ligand Summary
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
UNII: 78E4J5IB5J
PubChem: 4211
ChEMBL: CHEMBL1670
DrugCentral: 1820
LyCHI: SQALPCX5Y21A
Target Activities
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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INHIBITOR | ||||||