metoclopramide
A dopamine D2 antagonist that is used as an antiemetic.
Synonym
Target Relevance
| 5-hydroxytryptamine receptor 3C | Tchem |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| 5-hydroxytryptamine receptor 4 | Tclin |
| AGONIST 399 | |
| pEC50 7770 | 6.0 |
| pEC50 7770 | 6.0 |
| pEC50 7770 | 6.0 |
| D(2) dopamine receptor | Tclin |
| ANTAGONIST 310 | |
| pKi 69794 | 7.1938 |
| pKi 69794 | 7.1938 |
| pKi 69794 | 7.1938 |
| pKi 69794 | 7.38 |
| 5-hydroxytryptamine receptor 3A | Tclin |
| ANTAGONIST 310 | |
| pKi 69794 | 6.699 |
| pKi 69794 | 6.699 |
| pKi 69794 | 6.699 |
| 5-hydroxytryptamine receptor 3E | Tchem |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| D(3) dopamine receptor | Tclin |
| pKi 69794 | 7.17 |
| 5-hydroxytryptamine receptor 3D | Tchem |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| Cytochrome P450 2D6 | Tclin |
| pIC50 141091 | 6.1 |
| 5-hydroxytryptamine receptor 3B | Tchem |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
| pKd 2647 | 7.30000019 |
Molecular Definition
| Canonical SMILES | CCN(CC)CCNC(=O)C1=C(OC)C=C(N)C(Cl)=C1 |
| Formula | C14H22ClN3O2 |
| Molecular Weight | 299.80 da |
| Stereocenters | 0/0 |