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macitentan

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
an endothelin receptor antagonist that prevents the binding of ET-1 to both ETA and ETB receptors, macitentan displays high affinity and sustained occupancy of the ET receptors in human pulmonary arterial smooth muscle cells
Synonyms & Links
Guide to Pharmacology: 7352
DrugCentral: 4809
LyCHI:  RCSNMFR4CQSF


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Target Activities