loperamide
Ligand Summary
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
UNII: 6X9OC3H4II
PubChem: 3955
PubChem: 43833345
Guide to Pharmacology: 7215
ChEMBL: CHEMBL841
ChEMBL: CHEMBL1707
DrugCentral: 1599
LyCHI: WXFXAH3QBV55
Target Activities
11 Activities
Items per page:
1 – 10 of 11
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | ||||||
Ki | ||||||
IC50 | ||||||
IC50 | ||||||
IC50 | ||||||
Ki | ||||||
Ki | ||||||
IC50 | ||||||
IC50 | ||||||
AC50 | ||||||