lifitegrast
Ligand Summary
a lymphocyte function-associated antigen-1 ( LFA-1) antagonist, blocks the interaction of LFA-1 with its cognate ligand intercellular adhesion molecule-1 (ICAM-1), LFA-1/ICAM-1 interaction can contribute to the formation of an immunological synapse resulting in T-cell activation and migration to target tissues
UNII: 038E5L962W
PubChem: 11965427
ChEMBL: CHEMBL2048028
DrugCentral: 5174
LyCHI: C9YDLSNCJUPD
Target Activities
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | ||||||
IC50 | ANTAGONIST | |||||
IC50 | ANTAGONIST | |||||
IC50 | ||||||