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erdafitinib

Ligand Summary
Ligand Structure
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Description
Erdafitinib inhibited FGFR phosphorylation and signaling and decreased cell viability in cell lines expressing FGFR genetic alterations, including point mutations, amplifications, and fusions. Erdafitinib demonstrated antitumor activity in FGFR-expressing cell lines and xenograft models derived from tumor types, including bladder cancer.
Synonyms & Links
Guide to Pharmacology: 9039
DrugCentral: 5327
LyCHI:  YQ15HNNJQ6JG


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Target Activities