Target Relevance

Tyrosyl-DNA phosphodiesterase 1 Tchem
Potency 2975 6.5
Equilibrative nucleoside transporter 1 Tclin
INHIBITOR 471
pKi 69787 8.5
pIC50 141067 6.84
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Tchem
pKi 69787 6.4
pKi 69787 6.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Tclin
INHIBITOR 471
pIC50 141067 4.35
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Tclin
INHIBITOR 471
pKi 69787 6.9
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Tclin
INHIBITOR 471
pKi 69787 6.22
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Tclin
INHIBITOR 471
pKi 69787 6.9
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' Tclin
INHIBITOR 471
pKi 69787 6.9
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Tclin
INHIBITOR 471
pKi 69787 6.9
cGMP-specific 3',5'-cyclic phosphodiesterase Tclin
INHIBITOR 471
pIC50 141067 6.28
pIC50 141067 6.24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Tclin
INHIBITOR 471
pIC50 141067 5.80161787
cGMP-dependent 3',5'-cyclic phosphodiesterase Tclin
INHIBITOR 471
pIC50 141067 5.49
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Tclin
INHIBITOR 471
pKi 69787 6.9
cAMP-specific 3',5'-cyclic phosphodiesterase 7B Tclin
INHIBITOR 471
pIC50 141067 6.0
pKi 69787 6.22
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Tclin
INHIBITOR 471
pIC50 141067 4.3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Tclin
INHIBITOR 471
pIC50 141067 4.35
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Tclin
INHIBITOR 471
pKi 69787 6.0
pKi 69787 6.0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B Tclin
INHIBITOR 471
pIC50 141067 4.37
Exopolyphosphatase PRUNE1 Tchem
pIC50 141067 6.11
pIC50 141067 6.11
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A Tclin
INHIBITOR 471
pIC50 141067 5.1

Molecular Definition

Canonical SMILES OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO
Formula C24H40N8O4
Molecular Weight 504.63 da
Stereocenters 0/0