Target Relevance

Tyrosyl-DNA phosphodiesterase 1 Tchem
Potency 2975 6.5
Equilibrative nucleoside transporter 1 Tclin
INHIBITOR 454
pKi 69794 8.5
pKi 69794 8.5
pKi 69794 8.5
pIC50 141091 6.84
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Tchem
pKi 69794 6.4
pKi 69794 6.4
pKi 69794 6.4
pKi 69794 6.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Tclin
INHIBITOR 454
pIC50 141091 4.35
pIC50 141091 4.35
pIC50 141091 4.35
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Tclin
INHIBITOR 454
pKi 69794 6.9
pKi 69794 6.9
pKi 69794 6.9
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Tclin
INHIBITOR 454
pKi 69794 6.22
pKi 69794 6.22
pKi 69794 6.22
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Tclin
INHIBITOR 454
pKi 69794 6.9
pKi 69794 6.9
pKi 69794 6.9
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' Tclin
INHIBITOR 454
pKi 69794 6.9
pKi 69794 6.9
pKi 69794 6.9
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Tclin
INHIBITOR 454
pKi 69794 6.9
pKi 69794 6.9
pKi 69794 6.9
cGMP-specific 3',5'-cyclic phosphodiesterase Tclin
INHIBITOR 454
pIC50 141091 6.28
pIC50 141091 6.28
pIC50 141091 6.28
pIC50 141091 6.24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Tclin
INHIBITOR 454
pIC50 141091 5.80161787
pIC50 141091 5.80161787
pIC50 141091 5.80161787
cGMP-dependent 3',5'-cyclic phosphodiesterase Tclin
INHIBITOR 454
pIC50 141091 5.49
pIC50 141091 5.49
pIC50 141091 5.49
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Tclin
INHIBITOR 454
pKi 69794 6.9
pKi 69794 6.9
pKi 69794 6.9
cAMP-specific 3',5'-cyclic phosphodiesterase 7B Tclin
INHIBITOR 454
pIC50 141091 6.0
pKi 69794 6.22
pIC50 141091 6.0
pKi 69794 6.22
pIC50 141091 6.0
pKi 69794 6.22
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Tclin
INHIBITOR 454
pIC50 141091 4.3
pIC50 141091 4.3
pIC50 141091 4.3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Tclin
INHIBITOR 454
pIC50 141091 4.35
pIC50 141091 4.35
pIC50 141091 4.35
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Tclin
INHIBITOR 454
pKi 69794 6.0
pKi 69794 6.0
pKi 69794 6.0
pKi 69794 6.0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B Tclin
INHIBITOR 454
pIC50 141091 4.37
pIC50 141091 4.37
pIC50 141091 4.37
Protein prune homolog Tchem
pIC50 141091 6.11
pIC50 141091 6.11
pIC50 141091 6.11
pIC50 141091 6.11
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A Tclin
INHIBITOR 454
pIC50 141091 5.1
pIC50 141091 5.1
pIC50 141091 5.1

Molecular Definition

Canonical SMILES OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO
Formula C24H40N8O4
Molecular Weight 504.63 da
Stereocenters 0/0