cocaine
Ligand Summary
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
UNII: I5Y540LHVR
PubChem: 446220
PubChem: 656832
Guide to Pharmacology: 2286
ChEMBL: CHEMBL370805
ChEMBL: CHEMBL529437
DrugCentral: 723
LyCHI: CUNKLPJ7P8L2
Target Activities
149 Activities
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