azelastine
Ligand Summary
Azelastine hydrochloride, a phthalazinone derivative, exhibits histamine H1-receptor antagonist activity in isolated tissues, animal models, and humans. Azelastine Hydrochloride is administered as a racemic mixture with no difference in pharmacologic activity noted between the enantiomers in in vitro studies. The major metabolite, desmethylazelastine, also possesses H1-receptor antagonist activity.
UNII: ZQI909440X
PubChem: 2267
Guide to Pharmacology: 7121
ChEMBL: CHEMBL639
DrugCentral: 271
LyCHI: VKY49BVV56A6
Target Activities
21 Activities
Items per page:
1 – 10 of 21
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