apremilast
Ligand Summary
Apremilast is an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4) specific for cyclic adenosine monophosphate (cAMP). PDE4 inhibition results in increased intracellular cAMP levels. The specific mechanism(s) by which apremilast exerts its therapeutic action in psoriatic arthritis patients and psoriasis patients is not well defined.
UNII: UP7QBP99PN
PubChem: 11561674
Guide to Pharmacology: 7372
ChEMBL: CHEMBL514800
DrugCentral: 4829
LyCHI: GTQW8KGMM25B
Target Activities
13 Activities
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