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amitriptyline

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
Synonyms & Links
PubChem: 2160
Guide to Pharmacology: 200
DrugCentral: 180
LyCHI:  V5NVUP34ATWH


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Target Activities