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abatacept

Ligand Summary
Description
A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.
Synonyms & Links
ChEMBL: CHEMBL1201823
DrugCentral: 5089
LyCHI:  abatacept


Target Activities