telaprevir
Ligand Summary
Telaprevir is an inhibitor of the HCV NS3/4A serine protease, necessary for the proteolytic cleavage of the HCV encoded polyprotein into mature forms of the NS4A, NS4B, NS5A and NS5B proteins and essential for viral replication. In a biochemical assay, telaprevir inhibited the proteolytic activity of the recombinant HCV NS3 protease domain with an IC50 value of 10 nM.
UNII: 655M5O3W0U
PubChem: 3010818
Guide to Pharmacology: 7871
ChEMBL: CHEMBL231813
DrugCentral: 4173
LyCHI: 5LVPD4N283TN
Target Activities
14 Activities
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1 – 10 of 14
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