Disease

Carcinoma 11,493
ovarian cancer 8,520
osteosarcoma 7,950
psoriasis 6,694
medulloblastoma, large-cell 6,241
glioblastoma 5,792
atypical teratoid / rhabdoid tumor 5,112
lung cancer 4,740
ependymoma 4,679
group 3 medulloblastoma 4,104
adult high grade glioma 3,801
Breast cancer 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291
malignant mesothelioma 3,232
Astrocytoma, Pilocytic 3,081
primitive neuroectodermal tumor 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955
invasive ductal carcinoma 2,951
non-small cell lung cancer 2,890
oligodendroglioma 2,850
lung carcinoma 2,843
lung adenocarcinoma 2,716
Kidney cancer 2,613
astrocytic glioma 2,597
Cancer 2,499
pancreatic cancer 2,398
interstitial cystitis 2,312
subependymal giant cell astrocytoma 2,287
tuberculosis 2,010
pituitary cancer 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962
Pick disease 1,894
group 4 medulloblastoma 1,855
ulcerative colitis 1,819
ductal carcinoma in situ 1,745
diabetes mellitus 1,728
cystic fibrosis 1,696
breast carcinoma 1,638
colon cancer 1,478
Autosomal recessive predisposition 1,442
adrenocortical carcinoma 1,428
Multiple myeloma 1,332
Rheumatoid arthritis 1,191
juvenile dermatomyositis 1,187
Schizophrenia 1,160
acute quadriplegic myopathy 1,158
astrocytoma 1,146
primary pancreatic ductal adenocarcinoma 1,109
spina bifida 1,074
pediatric high grade glioma 1,064
nasopharyngeal carcinoma 1,058
cutaneous lupus erythematosus 1,057
Intellectual disability 1,016
dermatomyositis 966
Atopic dermatitis 952
active Crohn's disease 922
non primary Sjogren syndrome sicca 891
gastric carcinoma 807
Epilepsy 792
acute myeloid leukemia 783
Liver Cirrhosis, Experimental 769
Waldenstrons macroglobulinemia 765
active ulcerative colitis 764
esophageal adenocarcinoma 737
primary Sjogren syndrome 735
medulloblastoma 720
Melanoma 711
Obesity 678
progressive supranuclear palsy 676
Bipolar Disorder 666
aldosterone-producing adenoma 665
Alzheimer's disease 658
Mental Retardation 645
Low intelligence 645
Mental deficiency 645
Poor school performance 645
Dull intelligence 645
Global developmental delay 608
Cognitive delay 608
Mental and motor retardation 608
Liver cancer 604
Duchenne muscular dystrophy 601
Seizures 596
Muscle hypotonia 571
pancreatic carcinoma 562
fibroadenoma 559
hepatocellular carcinoma 547
Endometriosis 540
Multiple Sclerosis 540
Short stature 531
chronic rhinosinusitis 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510
Down syndrome 499
Prostatic Neoplasms 495
mucosa-associated lymphoid tissue lymphoma 484
Skin cancer 469
posterior fossa group A ependymoma 468
sonic hedgehog group medulloblastoma 467
gastric cancer 459

Ligand

CHEMBL388978 200
CHEMBL603469 122
CHEMBL1230609 63
CHEMBL509032 58
metformin 50
sunitinib 50
dasatinib 47
CHEMBL574738 44
nintedanib 44
CHEMBL288441 42
CHEMBL475251 42
CHEMBL386051 40
guanidine 40
fampridine 40
amifampridine 40
bosutinib 39
CHEMBL42 27
halothane 25
CHEMBL715 25
isoflurane 24
topiramate 24
CHEMBL495727 23
desflurane 23
dipyridamole 23
sevoflurane 22
CHEMBL629 22
sorafenib 21
CHEMBL85 21
imatinib 21
lisuride 20
CHEMBL1112 20
chlorpromazine 20
clozapine 19
CHEMBL19611 19
tetraethylammonium 18
CHEMBL19215 18
CHEMBL249097 18
thioridazine 18
CHEMBL2347053 18
CHEMBL1908395 17
ibrutinib 17
CHEMBL1784637 17
methoxyflurane 17
CHEMBL1908397 17
CHEMBL516 17
verapamil 16
CHEMBL608533 16
CHEMBL384304 16
metharbital 16
talbutal 16
triclofos 16
thiamylal 16
halazepam 16
CHEMBL1909072 16
CHEMBL723 16
nilotinib 16
zotepine 15
cisapride 15
CHEMBL1721885 15
staurosporine 15
CHEMBL708 15
cabergoline 15
bromocriptine 15
CHEMBL494089 15
haloperidol 15
CHEMBL445813 15
nafamostat 14
Cd2+ 14
neratinib 14
acalabrutinib 14
voruciclib 14
CHEMBL491473 14
CHEMBL522892 14
mianserin 14
CHEMBL445 14
CHEMBL3217984 14
CHEMBL442 14
pergolide 14
ketanserin 14
CHEMBL415 14
CHEMBL3683258 14
CHEMBL716 14
CHEMBL99 13
CHEMBL1241674 13
orphenadrine 13
quinidine 13
nifedipine 13
ilomastat 13
CHEMBL1980297 13
MK-2461 13
midostaurin 13
triazolam 13
fospropofol 13
adinazolam 13
crizotinib 13
CHEMBL572878 13
terguride 13
spiperone 13
CHEMBL1201203 13
amitriptyline 13

Tissue

Endocrine System 18,159
Female tissues 17,400
Digestive Tract 17,369
Skin and soft tissues 17,230
Male tissues 17,142
Blood and immune system 16,909
Liver and Pancreas 16,750
Nervous System 16,725
Urinary Tract 16,678
Respiratory system 16,393
Cardiovascular System 15,192