Disease

ovarian cancer 8,484
osteosarcoma 7,933
psoriasis 6,683
medulloblastoma, large-cell 6,234
glioblastoma 5,572
lung cancer 4,466
atypical teratoid / rhabdoid tumor 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289
malignant mesothelioma 3,162
Breast cancer 3,094
pilocytic astrocytoma 3,086
primitive neuroectodermal tumor 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956
invasive ductal carcinoma 2,950
oligodendroglioma 2,849
lung carcinoma 2,844
non-small cell lung cancer 2,798
lung adenocarcinoma 2,713
pediatric high grade glioma 2,712
ependymoma 2,514
Cancer 2,346
pancreatic cancer 2,300
interstitial cystitis 2,299
subependymal giant cell astrocytoma 2,287
group 3 medulloblastoma 2,254
astrocytic glioma 2,241
adult high grade glioma 2,148
Carcinoma 2,147
ulcerative colitis 2,085
pituitary cancer 1,972
Pick disease 1,893
group 4 medulloblastoma 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795
ductal carcinoma in situ 1,745
cystic fibrosis 1,665
diabetes mellitus 1,663
breast carcinoma 1,614
tuberculosis 1,557
posterior fossa group B ependymoma 1,530
medulloblastoma 1,524
posterior fossa group A ependymoma 1,511
astrocytoma 1,493
sonic hedgehog group medulloblastoma 1,482
colon cancer 1,475
adrenocortical carcinoma 1,427
Multiple myeloma 1,327
primary pancreatic ductal adenocarcinoma 1,271
juvenile dermatomyositis 1,189
Rheumatoid Arthritis 1,157
acute quadriplegic myopathy 1,157
atypical teratoid/rhabdoid tumor 1,095
spina bifida 1,064
cutaneous lupus erythematosus 1,056
nasopharyngeal carcinoma 1,056
Atopic dermatitis 942
dermatomyositis 933
active Crohn's disease 918
non primary Sjogren syndrome sicca 840
gastric carcinoma 832
primary Sjogren syndrome 789
acute myeloid leukemia 780
Waldenstrons macroglobulinemia 765
esophageal adenocarcinoma 737
tuberculosis and treatment for 6 months 686
progressive supranuclear palsy 674
aldosterone-producing adenoma 664
Alzheimer's disease 644
Obesity 616
Duchenne muscular dystrophy 602
Intellectual disability 573
pancreatic carcinoma 567
fibroadenoma 557
Down syndrome 548
Endometriosis 534
hepatocellular carcinoma 532
chronic rhinosinusitis 512
Schizophrenia 500
autosomal dominant Emery-Dreifuss muscular dystrophy 499
Multiple Sclerosis 496
mucosa-associated lymphoid tissue lymphoma 480
active ulcerative colitis 477
Prostatic Neoplasms 471
IGA Glomerulonephritis 454
Amyotrophic Lateral Sclerosis 431
gastric cancer 430
non-small cell lung carcinoma 413
Mammary Neoplasms 410
inflammatory breast cancer 404
Kidney disease 396
Neurodegenerative disease 383
Parkinson's disease 364
sarcoidosis 356
Asthma 347
glioblastoma multiforme 347
Epilepsy 346
Polycystic Ovary Syndrome 332
nephrosclerosis 329
tuberculosis and treatment for 3 months 327
Autistic Disorder 320

Ligand

CHEMBL388978 330
CHEMBL603469 278
CHEMBL509032 205
CHEMBL475251 203
sunitinib 186
CHEMBL1908397 185
nintedanib 155
CHEMBL1230609 149
CHEMBL574738 148
CHEMBL1721885 148
CHEMBL1287853 134
CHEMBL608533 132
CHEMBL1241674 123
CHEMBL386051 116
bosutinib 114
CHEMBL522892 103
CHEMBL1908395 101
crizotinib 95
CHEMBL572878 91
CHEMBL379218 81
dasatinib 75
CHEMBL191003 66
CHEMBL450786 66
CHEMBL428690 63
CHEMBL1789941 61
CHEMBL180022 55
ruboxistaurin 55
sorafenib 54
CHEMBL103667 51
pazopanib 51
metformin 50
CHEMBL494089 49
CHEMBL491473 46
CHEMBL223360 44
CHEMBL1240703 44
vandetanib 43
CHEMBL607707 41
nilotinib 41
CHEMBL31965 40
guanidine 40
fampridine 40
amifampridine 40
CHEMBL464552 39
axitinib 39
CHEMBL296468 38
CHEMBL384304 37
CHEMBL230011 35
CHEMBL1908396 35
CHEMBL558752 32
CHEMBL445813 31
CHEMBL513909 31
CHEMBL300138 29
CHEMBL941 28
erlotinib 28
CHEMBL259084 27
clozapine 26
CHEMBL2205426 24
CHEMBL10 24
topiramate 24
olanzapine 24
CHEMBL495727 23
CHEMBL2436978 23
CHEMBL572881 23
desflurane 23
isoflurane 23
halothane 23
CHEMBL3217984 23
CHEMBL3683258 22
CHEMBL460472 22
CHEMBL1784637 22
CHEMBL377300 22
CHEMBL215152 22
sevoflurane 22
dipyridamole 22
CHEMBL249097 22
CHEMBL1230020 21
CHEMBL590109 21
CHEMBL6437 21
chlorpromazine 21
CHEMBL2347053 21
CHEMBL1725279 20
CHEMBL576982 20
CHEMBL2010872 20
CHEMBL19215 20
CHEMBL1908391 20
risperidone 20
aripiprazole 20
orphenadrine 19
CHEMBL19611 19
CHEMBL278041 19
CHEMBL2148120 19
CHEMBL64894 19
CHEMBL954 18
CHEMBL1980297 18
CHEMBL1090360 18
CHEMBL2151321 18
lisuride 18
CHEMBL1082152 18
flunarizine 18
thioridazine 18

Tissue

Female tissues 18,647
Nervous System 18,561
Endocrine System 18,512
Digestive Tract 18,473
Urinary Tract 18,444
Liver and Pancreas 18,136
Skin and soft tissues 18,115
Blood and immune system 17,995
Male tissues 17,969
Cardiovascular System 17,958
Respiratory system 17,484