Currently the diseases view is a work in progress and should not be considered a definitive resource yet

Development Level

Tclin 1,123
Tchem 746
Tbio 328
Tdark 147

Target Family

Enzyme 733
Non-IDG 582
GPCR 532
Nuclear Receptor 363
Ion Channel 330
Transporter 297
Kinase 232
Transcription Factor 195
Epigenetic 96
TF/Epigenetic 37
oGPCR 25

Drug

ciprofloxacin 85
prednisolone 65
lidocaine 16
progesterone 13
heparin 10
itraconazole 10
testosterone 10
hydroxychloroquine 8
phenylephrine 8
vinblastine 8
diclofenac 7
alprostadil 6
benzocaine 6
ciclosporin 6
cilastatin 6
cimetidine 6
dexamethasone 6
metoclopramide 6
theophylline 6
allopurinol 5
amantadine 5
bevacizumab 5
cortisone acetate 5
dinoprostone 5
doxorubicin 5
lamotrigine 5
liothyronine 5
phentolamine 5
ropivacaine 5
tretinoin 5
aflibercept 4
aripiprazole 4
cetuximab 4
diazepam 4
dobutamine 4
docetaxel 4
flavoxate 4
ibrutinib 4
imatinib 4
isoprenaline 4
midazolam 4
naloxone 4
paclitaxel 4
pregabalin 4
pyrimethamine 4
tacrolimus 4
vincristine 4
ziconotide 4
acetazolamide 3
amlodipine 3
asenapine 3
bumetanide 3
calcitriol 3
carmustine 3
clotrimazole 3
dasatinib 3
dicoumarol 3
dipyridamole 3
edrophonium 3
epinephrine 3
ezetimibe 3
famotidine 3
filgrastim 3
flumazenil 3
glyceryl trinitrate 3
glycopyrronium bromide 3
hydroxycarbamide 3
ketoconazole 3
lodoxamide 3
lorazepam 3
losartan 3
methotrexate 3
mupirocin 3
naproxen 3
niclosamide 3
nicotine 3
niraparib 3
palifermin 3
pilocarpine 3
promazine 3
propranolol 3
ranitidine 3
retinol 3
spironolactone 3
tazarotene 3
tocilizumab 3
verapamil 3
zoledronic acid 3
baclofen 2
canakinumab 2
clozapine 2
droperidol 2
eculizumab 2
floxuridine 2
modafinil 2
norepinephrine 2
pamidronic acid 2
prochlorperazine 2
thiopental 2
vitamin A palmitate 2

Data Source

DrugCentral Indication 1,224
TCRDv5.1.0 19,624
DisGeNET 12,284
CTD 5,577
Monarch 5,019
JensenLab Text Mining 4,079
JensenLab Knowledge GHR 694
JensenLab Experiment DistiLD 209
Expression Atlas 142
JensenLab Knowledge UniProtKB-... 119
JensenLab Experiment COSMIC 83

DisGeNET Source

HPO 158
CTD_human 149
CTD_human;HPO 35
ORPHANET 16
PSYGENET 12
CTD_human;ORPHANET 8
CTD_human;PSYGENET 4
CTD_human;HPO;ORPHANET 3
CTD_human;HPO;UNIPROT 3
HPO;ORPHANET 3
HPO;PSYGENET 3
CTD_human;HPO;ORPHANET;UNIPROT... 2
HPO;ORPHANET;UNIPROT 2
CTD_human;HPO;PSYGENET 1
CTD_human;ORPHANET;UNIPROT 1
CTD_human;UNIPROT 1
HPO;UNIPROT 1
ORPHANET;UNIPROT 1
UNIPROT 1