Currently the diseases view is a work in progress and should not be considered a definitive resource yet

Development Level

Tclin 1,120
Tchem 729
Tbio 287
Tdark 144

Target Family

Enzyme 717
Non-IDG 552
GPCR 521
Nuclear Receptor 349
Ion Channel 314
Transporter 272
Kinase 186
Transcription Factor 157
Epigenetic 63
TF/Epigenetic 28
oGPCR 22

Drug

ciprofloxacin 86
prednisolone 68
lidocaine 16
progesterone 13
testosterone 11
heparin 10
itraconazole 10
hydroxychloroquine 8
vinblastine 8
alprostadil 7
diclofenac 7
phenylephrine 7
benzocaine 6
bevacizumab 6
ciclosporin 6
cilastatin 6
cimetidine 6
cortisone acetate 6
dexamethasone 6
metoclopramide 6
theophylline 6
tretinoin 6
allopurinol 5
amantadine 5
diazepam 5
dinoprostone 5
doxorubicin 5
flavoxate 5
lamotrigine 5
liothyronine 5
paclitaxel 5
phentolamine 5
ropivacaine 5
vincristine 5
acetazolamide 4
aflibercept 4
aripiprazole 4
beclometasone dipropionate 4
cetuximab 4
citric acid 4
dobutamine 4
docetaxel 4
ezetimibe 4
imatinib 4
isoprenaline 4
midazolam 4
naloxone 4
pregabalin 4
promazine 4
pyrimethamine 4
spironolactone 4
tacrolimus 4
ziconotide 4
amlodipine 3
asenapine 3
bumetanide 3
calcitriol 3
canakinumab 3
carmustine 3
chlordiazepoxide 3
clotrimazole 3
dasatinib 3
dicoumarol 3
dipyridamole 3
edrophonium 3
epinephrine 3
everolimus 3
famotidine 3
flumazenil 3
glyceryl trinitrate 3
glycopyrronium bromide 3
hydroxycarbamide 3
hyoscyamine 3
ibrutinib 3
ketoconazole 3
lodoxamide 3
lorazepam 3
losartan 3
meclozine 3
methotrexate 3
mupirocin 3
naproxen 3
niclosamide 3
nicotine 3
palifermin 3
pentobarbital 3
pilocarpine 3
propranolol 3
ranitidine 3
retinol 3
tazarotene 3
tetracosactide 3
trimetaphan 3
verapamil 3
zoledronic acid 3
clozapine 2
droperidol 2
norepinephrine 2
pamidronic acid 2
prochlorperazine 2

Data Source

DrugCentral Indication 1,226
TCRDv4.6.9 15,277
DisGeNET 6,981
Monarch 5,121
UniProt Disease 4,541
JensenLab Text Mining 3,592
DrugCentral 1,012
JensenLab Knowledge GHR 498
JensenLab Experiment DistiLD 206
Expression Atlas 141
JensenLab Knowledge UniProtKB-... 120
JensenLab Experiment COSMIC 63

DisGeNET Source

CTD_human 163
GWASCAT 51
CLINVAR 34
ORPHANET 28
UNIPROT 7